Sunday, 25 December 2011

Luminalum




Luminalum may be available in the countries listed below.


Ingredient matches for Luminalum



Phenobarbital

Phenobarbital is reported as an ingredient of Luminalum in the following countries:


  • Poland

International Drug Name Search

Wednesday, 21 December 2011

Miansérine Arrow




Miansérine Arrow may be available in the countries listed below.


Ingredient matches for Miansérine Arrow



Mianserin

Mianserin hydrochloride (a derivative of Mianserin) is reported as an ingredient of Miansérine Arrow in the following countries:


  • France

International Drug Name Search

Saturday, 17 December 2011

Erythrocine-ES




Erythrocine-ES may be available in the countries listed below.


Ingredient matches for Erythrocine-ES



Erythromycin

Erythromycin ethylsuccinate (a derivative of Erythromycin) is reported as an ingredient of Erythrocine-ES in the following countries:


  • Netherlands

International Drug Name Search

Wednesday, 14 December 2011

Cliniderm




Cliniderm may be available in the countries listed below.


Ingredient matches for Cliniderm



Salicylic Acid

Salicylic Acid is reported as an ingredient of Cliniderm in the following countries:


  • Switzerland

Triclosan

Triclosan is reported as an ingredient of Cliniderm in the following countries:


  • Switzerland

International Drug Name Search

Tuesday, 13 December 2011

Clemispray




Clemispray may be available in the countries listed below.


In some countries, this medicine may only be approved for veterinary use.

Ingredient matches for Clemispray



Chlorhexidine

Chlorhexidine digluconate (a derivative of Chlorhexidine) is reported as an ingredient of Clemispray in the following countries:


  • France

International Drug Name Search

Saturday, 10 December 2011

Siccalactin




Siccalactin may be available in the countries listed below.


In some countries, this medicine may only be approved for veterinary use.

Ingredient matches for Siccalactin



Benzylpenicillin

Benzylpenicillin benzathine (a derivative of Benzylpenicillin) is reported as an ingredient of Siccalactin in the following countries:


  • Sweden

Dihydrostreptomycin

Dihydrostreptomycin sulfate (a derivative of Dihydrostreptomycin) is reported as an ingredient of Siccalactin in the following countries:


  • Sweden

International Drug Name Search

Tuesday, 6 December 2011

Enalapril / Hydrochlorothiazide Arrow




Enalapril/Hydrochlorothiazide Arrow may be available in the countries listed below.


Ingredient matches for Enalapril/Hydrochlorothiazide Arrow



Enalapril

Enalapril maleate (a derivative of Enalapril) is reported as an ingredient of Enalapril/Hydrochlorothiazide Arrow in the following countries:


  • France

Hydrochlorothiazide

Hydrochlorothiazide is reported as an ingredient of Enalapril/Hydrochlorothiazide Arrow in the following countries:


  • France

International Drug Name Search

Monday, 5 December 2011

Pred Forte


Pred Forte is a brand name of prednisolone ophthalmic, approved by the FDA in the following formulation(s):


PRED FORTE (prednisolone acetate - suspension/drops; ophthalmic)



  • Manufacturer: ALLERGAN

    Approved Prior to Jan 1, 1982

    Strength(s): 1% [RLD][AB]

Has a generic version of Pred Forte been approved?


Yes. The following products are equivalent to Pred Forte:


OMNIPRED (prednisolone acetate suspension/drops; ophthalmic)



  • Manufacturer: ALCON

    Approved Prior to Jan 1, 1982

    Strength(s): 1% [AB]

Note: Fraudulent online pharmacies may attempt to sell an illegal generic version of Pred Forte. These medications may be counterfeit and potentially unsafe. If you purchase medications online, be sure you are buying from a reputable and valid online pharmacy. Ask your health care provider for advice if you are unsure about the online purchase of any medication.

See also: About generic drugs.




Related Patents

There are no current U.S. patents associated with Pred Forte.

See also...

  • Pred Forte Drops Consumer Information (Wolters Kluwer)
  • Pred Forte Consumer Information (Cerner Multum)
  • Prednisolone Acetate Drops Consumer Information (Wolters Kluwer)
  • Prednisolone Sodium Phosphate Drops Consumer Information (Wolters Kluwer)
  • Prednisolone ophthalmic Consumer Information (Cerner Multum)
  • Prednisolone Acetate eent AHFS DI Monographs (ASHP)
  • Prednisolone Sodium Phosphate eent AHFS DI Monographs (ASHP)

Friday, 2 December 2011

Digestivo Giuliani




Digestivo Giuliani may be available in the countries listed below.


Ingredient matches for Digestivo Giuliani



Domperidone

Domperidone is reported as an ingredient of Digestivo Giuliani in the following countries:


  • Italy

International Drug Name Search

Thursday, 17 November 2011

Minirin / Ddavp




Minirin/Ddavp may be available in the countries listed below.


Ingredient matches for Minirin/Ddavp



Desmopressin

Desmopressin acetate (a derivative of Desmopressin) is reported as an ingredient of Minirin/Ddavp in the following countries:


  • Italy

International Drug Name Search

Sunday, 13 November 2011

Naristar




Naristar may be available in the countries listed below.


Ingredient matches for Naristar



Cetirizine

Cetirizine dihydrochloride (a derivative of Cetirizine) is reported as an ingredient of Naristar in the following countries:


  • Italy

Pseudoephedrine

Pseudoephedrine hydrochloride (a derivative of Pseudoephedrine) is reported as an ingredient of Naristar in the following countries:


  • Italy

International Drug Name Search

Saturday, 5 November 2011

Pheny-Pas-Tebamin




Ingredient matches for Pheny-Pas-Tebamin



Fenamisal

Fenamisal is reported as an ingredient of Pheny-Pas-Tebamin in the following countries:


  • United States

International Drug Name Search

Wednesday, 2 November 2011

Lyrinel




Lyrinel may be available in the countries listed below.


UK matches:

  • Lyrinel XL prolonged release tablet (SPC)

Ingredient matches for Lyrinel



Oxybutynin

Oxybutynin hydrochloride (a derivative of Oxybutynin) is reported as an ingredient of Lyrinel in the following countries:


  • Greece

  • Ireland

  • Israel

  • Luxembourg

  • Mexico

  • South Africa

  • United Kingdom

International Drug Name Search

Glossary

SPC Summary of Product Characteristics (UK)

Click for further information on drug naming conventions and International Nonproprietary Names.

Tuesday, 1 November 2011

Cekodin




Cekodin may be available in the countries listed below.


Ingredient matches for Cekodin



Cefradine

Cefradine is reported as an ingredient of Cekodin in the following countries:


  • Taiwan

International Drug Name Search

Friday, 28 October 2011

Antazoline




Scheme

Rec.INN

ATC (Anatomical Therapeutic Chemical Classification)

R01AC04,R06AX05

CAS registry number (Chemical Abstracts Service)

0000091-75-8

Chemical Formula

C17-H19-N3

Molecular Weight

265

Therapeutic Category

Histamine, H₁-receptor antagonist

Chemical Name

1H-Imidazole-2-methanamine, 4,5-dihydro-N-phenyl-N-(phenylmethyl)-

Foreign Names

  • Antazolinum (Latin)
  • Antazolin (German)
  • Antazoline (French)
  • Antazolina (Spanish)

Generic Names

  • Antazolina (OS: DCIT)
  • Antazoline (OS: BAN, DCF)
  • 5512-M (IS)
  • M 5512 (IS)
  • PM 265 (IS)
  • Antazoline Hydrochloride (OS: BANM)
  • Phenazoline hydrochloride (IS)
  • Antazoline (chlorhydrate d') (PH: Ph. Eur. 6)
  • Antazoline Hydrochloride (PH: BP 2010, USP XV, Ph. Eur. 6)
  • Antazolinhydrochlorid (PH: Ph. Eur. 6)
  • Antazolini hydrochloridum (PH: Ph. Int. 2, Ph. Eur. 6)
  • Antazoline Mesylate (IS)
  • Antazoline methanesulfonate (IS)
  • Antazoline Phosphate (OS: BANM)
  • Antazoline Phosphate (PH: USP 32)
  • Antazoline Sulphate (OS: BANM)
  • Antazolina solfato (PH: F.U. XII)

Brand Names

  • Phenazolinum
    Polfa Warszawa, Poland


  • Sesal (Antazoline and Naphazoline)
    Ophtha, Denmark


  • Spersallerg (Antazoline and Tetryzoline)
    Novartis, Slovenia


  • Apillerg (Antazoline and Tetryzoline)
    Amman Pharmaceutical Industries Co., Oman


  • Gemini (Antazoline and Tetryzoline)
    Adcock Ingram Pharmaceuticals, South Africa


  • Oculerge (Antazoline and Tetryzoline)
    Aspen Pharmacare Consumer, South Africa


  • Spersallerg (Antazoline and Tetryzoline)
    Adcock Ingram Pharmaceuticals, South Africa; Excelvision, Bulgaria; Novartis, Switzerland; Novartis, Germany; Novartis, Norway; Novartis, Oman; Novartis, Poland; Novartis, Slovakia


  • Sanorin-Analergin (Antazoline and Naphazoline)
    Ivax, Slovakia


  • Albalon A (Antazoline and Naphazoline)
    Allergan, New Zealand


  • Alergoftal (Antazoline and Naphazoline)
    Alcon, Spain; Alcon, Oman; Alcon Cusi, Poland


  • Allergopos (Antazoline and Tetryzoline)
    Ursapharm, Germany


  • Apihist (Antazoline and Naphazoline)
    Amman Pharmaceutical Industries Co., Oman


  • Vasocon-A (Antazoline and Naphazoline)
    Novartis, United States


  • Antasten-Privin (Antazoline and Naphazoline)
    Novartis Healthcare, Sweden


  • Antistin Privin (Antazoline and Naphazoline)
    Adcock Ingram Pharmaceuticals, South Africa; Novartis, Oman


  • Antistin Privina (Antazoline and Naphazoline)
    Novartis, Italy


  • Antistin-Privin (Antazoline and Naphazoline)
    Novartis, Switzerland; Novartis, Germany


  • Antistina-Privin (Antazoline and Naphazoline)
    Novartis, Denmark


  • Dermophenazol (Antazoline and Naphazoline)
    Polfa Warszawa, Poland


  • Noscam (Antazoline and Naphazoline)
    Riyad Pharma, Oman


  • Ocured (Antazoline and Naphazoline)
    Riyad Pharma, Oman


  • Ophtazolin (Antazoline and Naphazoline)
    Dar-Al-Dawa, Oman


  • Otrivine-Antistin (Antazoline and Xylometazoline)
    Novartis Consumer Health, United Kingdom; Novartis Consumer Health, Ireland


  • Rhinophenazol (Antazoline and Naphazolin Nitrat)
    Polfa Warszawa, Poland

International Drug Name Search

Glossary

BANBritish Approved Name
BANMBritish Approved Name (Modified)
DCFDénomination Commune Française
DCITDenominazione Comune Italiana
ISInofficial Synonym
OSOfficial Synonym
PHPharmacopoeia Name
Rec.INNRecommended International Nonproprietary Name (World Health Organization)

Click for further information on drug naming conventions and International Nonproprietary Names.

Thursday, 27 October 2011

Ibuprofen Merck




Ibuprofen Merck may be available in the countries listed below.


Ingredient matches for Ibuprofen Merck



Ibuprofen

Ibuprofen is reported as an ingredient of Ibuprofen Merck in the following countries:


  • Netherlands

International Drug Name Search

Monday, 24 October 2011

Hepasel




Hepasel may be available in the countries listed below.


Ingredient matches for Hepasel



Biphenyl dimethyl dicarboxylate

Biphenyl dimethyl dicarboxylate is reported as an ingredient of Hepasel in the following countries:


  • Myanmar

  • Vietnam

International Drug Name Search

Saturday, 15 October 2011

A-vitel




A-vitel may be available in the countries listed below.


Ingredient matches for A-vitel



Retinol

Retinol palmitate (a derivative of Retinol) is reported as an ingredient of A-vitel in the following countries:


  • Argentina

International Drug Name Search

Tuesday, 11 October 2011

Mométasone




Mométasone may be available in the countries listed below.


Ingredient matches for Mométasone



Mometasone

Mométasone (DCF) is known as Mometasone in the US.

International Drug Name Search

Glossary

DCFDénomination Commune Française

Click for further information on drug naming conventions and International Nonproprietary Names.

Sunday, 9 October 2011

Contrasal




Contrasal may be available in the countries listed below.


Ingredient matches for Contrasal



Dextromethorphan

Dextromethorphan hydrobromide (a derivative of Dextromethorphan) is reported as an ingredient of Contrasal in the following countries:


  • Bahrain

  • Egypt

  • Iraq

  • Jordan

  • Kuwait

  • Lebanon

  • Libya

  • Qatar

  • Saudi Arabia

  • Sudan

  • Syria

  • United Arab Emirates

  • Yemen

International Drug Name Search

Saturday, 8 October 2011

Dorover




Dorover may be available in the countries listed below.


Ingredient matches for Dorover



Perindopril

Perindopril erbumine (a derivative of Perindopril) is reported as an ingredient of Dorover in the following countries:


  • Vietnam

International Drug Name Search

Tuesday, 4 October 2011

Voltamicin




Voltamicin may be available in the countries listed below.


Ingredient matches for Voltamicin



Diclofenac

Diclofenac sodium salt (a derivative of Diclofenac) is reported as an ingredient of Voltamicin in the following countries:


  • Switzerland

Gentamicin

Gentamicin sulfate (a derivative of Gentamicin) is reported as an ingredient of Voltamicin in the following countries:


  • Switzerland

International Drug Name Search

Tuesday, 27 September 2011

Adco-Alzam




Adco-Alzam may be available in the countries listed below.


Ingredient matches for Adco-Alzam



Alprazolam

Alprazolam is reported as an ingredient of Adco-Alzam in the following countries:


  • South Africa

International Drug Name Search

Friday, 23 September 2011

Ciprofibrate Biogaran




Ciprofibrate Biogaran may be available in the countries listed below.


Ingredient matches for Ciprofibrate Biogaran



Ciprofibrate

Ciprofibrate is reported as an ingredient of Ciprofibrate Biogaran in the following countries:


  • France

International Drug Name Search

Thursday, 22 September 2011

Volulyte




Volulyte may be available in the countries listed below.


Ingredient matches for Volulyte



Hetastarch

Hetastarch is reported as an ingredient of Volulyte in the following countries:


  • Netherlands

  • Norway

  • Sweden

International Drug Name Search

Monday, 19 September 2011

Eurythmic




Eurythmic may be available in the countries listed below.


Ingredient matches for Eurythmic



Amiodarone

Amiodarone hydrochloride (a derivative of Amiodarone) is reported as an ingredient of Eurythmic in the following countries:


  • India

International Drug Name Search

Sunday, 28 August 2011

Dalacin C Palmitate



Generic Name: clindamycin (Oral route, Injection route, Intravenous route)

klin-da-MYE-sin

Intravenous route(Solution)

Pseudomembranous colitis has been reported with nearly all antibacterial agents, including clindamycin, and may range in severity from mild to life-threatening. Therefore, it is important to consider this diagnosis in patients who present with diarrhea subsequent to the administration of antibacterial agents. Because clindamycin therapy has been associated with severe colitis which may end fatally, it should be reserved for serious infections where less toxic antimicrobial agents are inappropriate. Diarrhea, colitis, and pseudomembranous colitis have been observed to begin up to several weeks following cessation of therapy with clindamycin .


Oral route(Powder for Solution)

Pseudomembranous colitis has been reported with nearly all antibacterial agents, including clindamycin, and may range in severity from mild to life-threatening. Therefore, it is important to consider this diagnosis in patients who present with diarrhea subsequent to the administration of antibacterial agents. Because clindamycin therapy has been associated with severe colitis which may end fatally, it should be reserved for serious infections where less toxic antimicrobial agents are inappropriate. Diarrhea, colitis, and pseudomembranous colitis have been observed to begin up to several weeks following cessation of therapy with clindamycin .


Oral route(Capsule)

Pseudomembranous colitis has been reported with nearly all antibacterial agents, including clindamycin, and may range in severity from mild to life-threatening. Therefore, it is important to consider this diagnosis in patients who present with diarrhea subsequent to the administration of antibacterial agents. Because clindamycin therapy has been associated with severe colitis which may end fatally, it should be reserved for serious infections where less toxic antimicrobial agents are inappropriate. Diarrhea, colitis, and pseudomembranous colitis have been observed to begin up to several weeks following cessation of therapy with clindamycin .



Commonly used brand name(s)

In the U.S.


  • Cleocin HCl

  • Cleocin Pediatric

  • Cleocin Phosphate IV

In Canada


  • Dalacin C Palmitate

Available Dosage Forms:


  • Solution

  • Powder for Solution

  • Capsule

Therapeutic Class: Antibiotic


Chemical Class: Lincosamide


Uses For Dalacin C Palmitate


Clindamycin is used to treat bacterial infections. It will not work for colds, flu, or other virus infections.


Clindamycin is available only with your doctor's prescription.


Before Using Dalacin C Palmitate


In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:


Allergies


Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.


Pediatric


This medicine has been tested in children and, in effective doses, has not been reported to cause different side effects or problems than it does in adults.


Geriatric


Many medicines have not been studied specifically in older people. Therefore, it may not be known whether they work exactly the same way they do in younger adults or if they cause different side effects or problems in older people. There is no specific information comparing use of clindamycin in the elderly with use in other age groups.


Pregnancy








Pregnancy CategoryExplanation
All TrimestersBAnimal studies have revealed no evidence of harm to the fetus, however, there are no adequate studies in pregnant women OR animal studies have shown an adverse effect, but adequate studies in pregnant women have failed to demonstrate a risk to the fetus.

Breast Feeding


Studies in women suggest that this medication poses minimal risk to the infant when used during breastfeeding.


Interactions with Medicines


Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.


Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.


  • Erythromycin

Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.


  • Atracurium

  • Cyclosporine

  • Metocurine

  • Tubocurarine

Interactions with Food/Tobacco/Alcohol


Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.


Other Medical Problems


The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:


  • Kidney disease (severe) or

  • Liver disease (severe)—Severe kidney or liver disease may increase blood levels of this medicine, increasing the chance of side effects

  • Stomach or intestinal disease, history of (especially colitis, including colitis caused by antibiotics, or enteritis)—Patients with a history of stomach or intestinal disease may have an increased chance of side effects

Proper Use of clindamycin

This section provides information on the proper use of a number of products that contain clindamycin. It may not be specific to Dalacin C Palmitate. Please read with care.


For patients taking the capsule form of clindamycin:


  • The capsule form of clindamycin should be taken with a full glass (8 ounces) of water or with meals to prevent irritation of the esophagus (tube between the throat and stomach).

For patients taking the oral liquid form of clindamycin:


  • Use a specially marked measuring spoon or other device to measure each dose accurately. The average household teaspoon may not hold the right amount of liquid.

  • Do not use after the expiration date on the label. The medicine may not work properly after this date. Check with your pharmacist if you have any questions about this.

To help clear up your infection completely, keep taking this medicine for the full time of treatment, even if you begin to feel better after a few days. If you have a ``strep'' infection, you should keep taking this medicine for at least 10 days. This is especially important in "strep" infections. Serious heart problems could develop later if your infection is not cleared up completely. Also, if you stop taking this medicine too soon, your symptoms may return.


This medicine works best when there is a constant amount in the blood. To help keep the amount constant, do not miss any doses. Also, it is best to take each dose at evenly spaced times day and night. For example, if you are to take 4 doses a day, doses should be spaced about 6 hours apart. If this interferes with your sleep or other daily activities, or if you need help in planning the best times to take your medicine, check with your health care professional.


Dosing


The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.


The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.


  • For bacterial infection:
    • For oral dosage forms (capsules and solution):
      • Adults and teenagers—150 to 300 milligrams (mg) every six hours.

      • Children—
        • Infants up to 1 month of age: Use and dose must be determined by your doctor.

        • Infants and children 1 month of age and older: Dose is based on body weight. The usual dose is 2 to 5 mg per kilogram (kg) (0.9 to 2.3 mg per pound) of body weight every six hours; or 2.7 to 6.7 mg per kg (1.2 to 3.0 mg per pound) of body weight every eight hours.



    • For injection dosage form:
      • Adults and teenagers—300 to 600 mg every six to eight hours injected into a muscle or vein; or 900 mg every eight hours injected into a muscle or vein.

      • Children—
        • Infants up to 1 month of age: Dose is based on body weight. The usual dose is 3.75 to 5 mg per kg (1.7 to 2.3 mg per pound) of body weight every six hours injected into a muscle or vein; or 5 to 6.7 mg per kg (2.3 to 3.0 mg per pound) of body weight every eight hours injected into a muscle or vein.

        • Infants and children 1 month of age and older: Dose is based on body weight. The usual dose is 3.75 to 10 mg per kg (1.7 to 4.5 mg per pound) of body weight every six hours injected into a muscle or vein; or 5 to 13.3 mg per kg (2.3 to 6.0 mg per pound) of body weight every eight hours injected into a muscle or vein.




Missed Dose


If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.


Storage


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.


Keep out of the reach of children.


Do not keep outdated medicine or medicine no longer needed.


Do not refrigerate the oral liquid form of clindamycin. If chilled, the liquid may thicken and be difficult to pour. Follow the directions on the label.


Precautions While Using Dalacin C Palmitate


It is important that your doctor check your progress at regular visits.


If your symptoms do not improve within a few days, or if they become worse, check with your doctor.


In some patients, clindamycin may cause diarrhea.


  • Severe diarrhea may be a sign of a serious side effect. Do not take any diarrhea medicine without first checking with your doctor . Diarrhea medicines, such as loperamide (Imodium A-D) or diphenoxylate and atropine (Lomotil), may make your diarrhea worse or make it last longer.

  • For mild diarrhea, diarrhea medicine containing attapulgite (e.g., Kaopectate tablets, Diasorb) may be taken. However, attapulgite may keep clindamycin from being absorbed into the body. Therefore, these diarrhea medicines should be taken at least 2 hours before or 3 to 4 hours after you take clindamycin by mouth.

  • If you have any questions about this or if mild diarrhea continues or gets worse, check with your health care professional.

Before having surgery (including dental surgery) with a general anesthetic, tell the medical doctor or dentist in charge that you are taking clindamycin.


Dalacin C Palmitate Side Effects


Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.


Check with your doctor immediately if any of the following side effects occur:


More common

(the above side effects may also occur up to several weeks after you stop taking this medicine)


  • Abdominal or stomach cramps and pain (severe)

  • abdominal tenderness

  • diarrhea (watery and severe), which may also be bloody

  • fever

Less common
  • Sore throat and fever

  • skin rash, redness, and itching

  • unusual bleeding or bruising

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:


More common
  • Diarrhea (mild)

  • nausea and vomiting

  • stomach pain

Less common
  • Itching of rectal, or genital (sex organ) areas

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.


Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.



The information contained in the Thomson Reuters Micromedex products as delivered by Drugs.com is intended as an educational aid only. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you.


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More Dalacin C Palmitate resources


  • Dalacin C Palmitate Use in Pregnancy & Breastfeeding
  • Drug Images
  • Dalacin C Palmitate Drug Interactions
  • Dalacin C Palmitate Support Group
  • 79 Reviews for Dalacin C Palmitate - Add your own review/rating


Compare Dalacin C Palmitate with other medications


  • Aspiration Pneumonia
  • Babesiosis
  • Bacteremia
  • Bacterial Endocarditis Prevention
  • Bacterial Infection
  • Bacterial Vaginitis
  • Bone infection
  • Deep Neck Infection
  • Diverticulitis
  • Intraabdominal Infection
  • Joint Infection
  • Malaria
  • Pelvic Inflammatory Disease
  • Peritonitis
  • Pneumocystis Pneumonia
  • Pneumonia
  • Prevention of Perinatal Group B Streptococcal Disease
  • Sinusitis
  • Skin Infection
  • Surgical Prophylaxis
  • Toxoplasmosis
  • Toxoplasmosis, Prophylaxis

Thursday, 18 August 2011

Frubiase




Frubiase may be available in the countries listed below.


Ingredient matches for Frubiase



Calcium

Calcium mixture of several salts (a derivative of Calcium) is reported as an ingredient of Frubiase in the following countries:


  • Germany

International Drug Name Search

Friday, 12 August 2011

Yellon




Yellon may be available in the countries listed below.


Ingredient matches for Yellon



Escin

Escin is reported as an ingredient of Yellon in the following countries:


  • Czech Republic

International Drug Name Search

Thursday, 11 August 2011

RE OB Plus DHA


Generic Name: prenatal multivitamins (PRE nay tal VYE ta mins)

Brand Names: Advance Care Plus, Bright Beginnings, Cavan Folate, Cavan One, Cavan-Heme OB, Cenogen Ultra, CitraNatal Rx, Co Natal FA, Complete Natal DHA, Complete-RF, CompleteNate, Concept OB, Docosavit, Dualvit OB, Duet, Edge OB, Elite OB 400, Femecal OB, Folbecal, Folcaps Care One, Folivan-OB, Foltabs, Gesticare, Icar Prenatal, Icare Prenatal Rx, Inatal Advance, Infanate DHA, Kolnatal DHA, Lactocal-F, Marnatal-F, Maternity, Maxinate, Mission Prenatal, Multi-Nate 30, Multinatal Plus, Nata 29 Prenatal, Natachew, Natafort, Natelle, Neevo, Nestabs, Nexa Select with DHA, Novanatal, NovaStart, O-Cal Prenatal, OB Complete, OB Natal One, Ob-20, Obtrex DHA, OptiNate, Paire OB Plus DHA, PNV Select, PNV-Total, PR Natal 400, Pre-H-Cal, Precare, PreferaOB, Premesis Rx, PrenaCare, PrenaFirst, PrenaPlus, Prenatabs OBN, Prenatabs Rx, Prenatal 1 Plus 1, Prenatal Elite, Prenatal Multivitamins, Prenatal Plus, Prenatal S, Prenatal-U, Prenate Advanced Formula, Prenate DHA, Prenate Elite, Prenavite FC, PreNexa, PreQue 10, Previte Rx, PrimaCare, Pruet DHA, RE OB Plus DHA, Renate, RightStep, Rovin-NV, Se-Care, Se-Natal One, Se-Plete DHA, Se-Tan DHA, Select-OB, Seton ET, Strongstart, Stuart Prenatal with Beta Carotene, Tandem OB, Taron-BC, Tri Rx, TriAdvance, TriCare, Trimesis Rx, Trinate, Triveen-PRx RNF, UltimateCare Advance, Ultra-Natal, Vemavite PRX 2, VeNatal FA, Verotin-BY, Verotin-GR, Vinacal OR, Vinatal Forte, Vinate Advanced (New Formula), Vinate AZ, Vinate Care, Vinate Good Start, Vinate II (New Formula), Vinate III, Vinate One, Vitafol-OB, VitaNatal OB plus DHA, Vitaphil, Vitaphil Aide, Vitaphil Plus DHA, Vitaspire, Viva DHA, Vol-Nate, Vol-Plus, Vol-Tab Rx, Vynatal F.A., Zatean-CH, Zatean-PN


What are RE OB Plus DHA (prenatal multivitamins)?

There are many brands and forms of prenatal vitamin available and not all brands are listed on this leaflet.


Prenatal vitamins are a combination of many different vitamins that are normally found in foods and other natural sources.


Prenatal vitamins are used to provide the additional vitamins needed during pregnancy. Minerals may also be contained in prenatal multivitamins.


Prenatal vitamins may also be used for purposes not listed in this medication guide.


What is the most important information I should know about prenatal vitamins?


There are many brands and forms of prenatal vitamin available and not all brands are listed on this leaflet.


Never take more than the recommended dose of a multivitamin. Avoid taking any other multivitamin product within 2 hours before or after you take your prenatal vitamins. Taking similar vitamin products together at the same time can result in a vitamin overdose or serious side effects.

Many multivitamin products also contain minerals such as calcium, iron, magnesium, potassium, and zinc. Minerals (especially taken in large doses) can cause side effects such as tooth staining, increased urination, stomach bleeding, uneven heart rate, confusion, and muscle weakness or limp feeling. Read the label of any multivitamin product you take to make sure you are aware of what it contains.


Seek emergency medical attention if you think you have used too much of this medicine. An overdose of vitamins A, D, E, or K can cause serious or life-threatening side effects and can also harm your unborn baby. Certain minerals contained in a prenatal multivitamin may also cause serious overdose symptoms or harm to the baby if you take too much.

Overdose symptoms may include stomach pain, vomiting, diarrhea, constipation, loss of appetite, hair loss, peeling skin, tingly feeling in or around your mouth, changes in menstrual periods, weight loss, severe headache, muscle or joint pain, severe back pain, blood in your urine, pale skin, and easy bruising or bleeding.


Do not take this medication with milk, other dairy products, calcium supplements, or antacids that contain calcium. Calcium may make it harder for your body to absorb certain ingredients of the multivitamin.

What should I discuss with my healthcare provider before taking prenatal vitamins?


Many vitamins can cause serious or life-threatening side effects if taken in large doses. Do not take more of this medication than directed on the label or prescribed by your doctor.

Before taking prenatal vitamins, tell your doctor about all of your medical conditions.


You may need to continue taking prenatal vitamins if you breast-feed your baby. Ask your doctor about taking this medication while breast-feeding.

How should I take prenatal vitamins?


Use exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended.


Never take more than the recommended dose of prenatal vitamins.

Many multivitamin products also contain minerals such as calcium, iron, magnesium, potassium, and zinc. Minerals (especially taken in large doses) can cause side effects such as tooth staining, increased urination, stomach bleeding, uneven heart rate, confusion, and muscle weakness or limp feeling. Read the label of any multivitamin product you take to make sure you are aware of what it contains.


Take your prenatal vitamin with a full glass of water.

Swallow the regular tablet or capsule whole. Do not break, chew, crush, or open it.


The chewable tablet must be chewed or allowed to dissolve in your mouth before swallowing. You may also allow the chewable tablet to dissolve in drinking water, fruit juice, or infant formula (but not milk or other dairy products). Drink this mixture right away.


Use prenatal vitamins regularly to get the most benefit. Get your prescription refilled before you run out of medicine completely.


Store at room temperature away from moisture and heat. Keep prenatal vitamins in their original container. Storing vitamins in a glass container can ruin the medication.

What happens if I miss a dose?


Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.


What happens if I overdose?


Seek emergency medical attention if you think you have used too much of this medicine. An overdose of vitamins A, D, E, or K can cause serious or life-threatening side effects and can also harm your unborn baby. Certain minerals contained in a prenatal multivitamin may also cause serious overdose symptoms or harm to the baby if you take too much.

Overdose symptoms may include stomach pain, vomiting, diarrhea, constipation, loss of appetite, hair loss, peeling skin, tingly feeling in or around your mouth, changes in menstrual periods, weight loss, severe headache, muscle or joint pain, severe back pain, blood in your urine, pale skin, and easy bruising or bleeding.


What should I avoid while taking prenatal vitamins?


Avoid taking any other multivitamin product within 2 hours before or after you take your prenatal vitamins. Taking similar vitamin products together at the same time can result in a vitamin overdose or serious side effects.

Avoid the regular use of salt substitutes in your diet if your multivitamin contains potassium. If you are on a low-salt diet, ask your doctor before taking a vitamin or mineral supplement.


Do not take this medication with milk, other dairy products, calcium supplements, or antacids that contain calcium. Calcium may make it harder for your body to absorb certain ingredients of the prenatal vitamin.

Prenatal vitamins side effects


Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

When taken as directed, prenatal vitamins are not expected to cause serious side effects. Less serious side effects may include:



  • upset stomach;




  • headache; or




  • unusual or unpleasant taste in your mouth.



This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.


What other drugs will affect prenatal vitamins?


Vitamin and mineral supplements can interact with certain medications, or affect how medications work in your body. Before taking a prenatal vitamin, tell your doctor if you also use:



  • diuretics (water pills);




  • heart or blood pressure medications;




  • tretinoin (Vesanoid);




  • isotretinoin (Accutane, Amnesteen, Clavaris, Sotret);




  • trimethoprim and sulfamethoxazole (Cotrim, Bactrim, Gantanol, Gantrisin, Septra, TMP/SMX); or




  • an NSAID (non-steroidal anti-inflammatory drug) such as ibuprofen (Advil, Motrin), naproxen (Aleve, Naprosyn, Naprelan, Treximet), celecoxib (Celebrex), diclofenac (Cataflam, Voltaren), indomethacin (Indocin), meloxicam (Mobic), and others.



This list is not complete and other drugs may interact with prenatal vitamins. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.



More RE OB Plus DHA resources


  • RE OB Plus DHA Use in Pregnancy & Breastfeeding
  • RE OB Plus DHA Drug Interactions
  • 0 Reviews for RE OB Plus DHA - Add your own review/rating


  • Cal-Nate MedFacts Consumer Leaflet (Wolters Kluwer)

  • CareNatal DHA MedFacts Consumer Leaflet (Wolters Kluwer)

  • CitraNatal 90 DHA MedFacts Consumer Leaflet (Wolters Kluwer)

  • CitraNatal Assure Prescribing Information (FDA)

  • CitraNatal Harmony Prescribing Information (FDA)

  • Concept DHA Prescribing Information (FDA)

  • Docosavit Prescribing Information (FDA)

  • Duet DHA with Ferrazone MedFacts Consumer Leaflet (Wolters Kluwer)

  • Folbecal MedFacts Consumer Leaflet (Wolters Kluwer)

  • Folcal DHA Prescribing Information (FDA)

  • Folcaps Care One Prescribing Information (FDA)

  • Gesticare DHA Prescribing Information (FDA)

  • Gesticare DHA MedFacts Consumer Leaflet (Wolters Kluwer)

  • Inatal Advance Prescribing Information (FDA)

  • Inatal Ultra Prescribing Information (FDA)

  • Multi-Nate DHA Prescribing Information (FDA)

  • Multi-Nate DHA Extra Prescribing Information (FDA)

  • MultiNatal Plus MedFacts Consumer Leaflet (Wolters Kluwer)

  • Natelle One Prescribing Information (FDA)

  • Neevo Caplets MedFacts Consumer Leaflet (Wolters Kluwer)

  • Neevo DHA MedFacts Consumer Leaflet (Wolters Kluwer)

  • OB Complete 400 MedFacts Consumer Leaflet (Wolters Kluwer)

  • Paire OB Plus DHA Prescribing Information (FDA)

  • PreNexa MedFacts Consumer Leaflet (Wolters Kluwer)

  • PreNexa Prescribing Information (FDA)

  • PreferaOB Prescribing Information (FDA)

  • Prenatal Plus Prescribing Information (FDA)

  • Prenatal Plus Iron Prescribing Information (FDA)

  • Prenate Elite Prescribing Information (FDA)

  • Prenate Elite MedFacts Consumer Leaflet (Wolters Kluwer)

  • Prenate Elite tablets

  • Prenate Essential Prescribing Information (FDA)

  • PrimaCare Advantage MedFacts Consumer Leaflet (Wolters Kluwer)

  • PrimaCare ONE capsules

  • PrimaCare One MedFacts Consumer Leaflet (Wolters Kluwer)

  • Renate DHA Prescribing Information (FDA)

  • Se-Natal 19 Chewable Tablets MedFacts Consumer Leaflet (Wolters Kluwer)

  • Se-Natal 19 Prescribing Information (FDA)

  • Tandem DHA Prescribing Information (FDA)

  • Tandem OB Prescribing Information (FDA)

  • TriAdvance Prescribing Information (FDA)

  • Triveen-One MedFacts Consumer Leaflet (Wolters Kluwer)

  • Triveen-PRx RNF Prescribing Information (FDA)

  • UltimateCare ONE NF Prescribing Information (FDA)

  • Ultra NatalCare MedFacts Consumer Leaflet (Wolters Kluwer)

  • Vinate AZ Prescribing Information (FDA)

  • Vitafol-One MedFacts Consumer Leaflet (Wolters Kluwer)

  • Zatean-CH Prescribing Information (FDA)



Compare RE OB Plus DHA with other medications


  • Vitamin/Mineral Supplementation during Pregnancy/Lactation


Where can I get more information?


  • Your pharmacist can provide more information about prenatal vitamins.


Wednesday, 10 August 2011

Aminophylline DF




Ingredient matches for Aminophylline DF



Aminophylline

Aminophylline is reported as an ingredient of Aminophylline DF in the following countries:


  • United States

International Drug Name Search

Tuesday, 2 August 2011

Amantadin AbZ




Amantadin AbZ may be available in the countries listed below.


Ingredient matches for Amantadin AbZ



Amantadine

Amantadine hydrochloride (a derivative of Amantadine) is reported as an ingredient of Amantadin AbZ in the following countries:


  • Germany

International Drug Name Search

Monday, 1 August 2011

Lacobile




Lacobile may be available in the countries listed below.


Ingredient matches for Lacobile



Ubidecarenone

Ubidecarenone is reported as an ingredient of Lacobile in the following countries:


  • Japan

International Drug Name Search

Saturday, 23 July 2011

Metenamina




Metenamina may be available in the countries listed below.


Ingredient matches for Metenamina



Methenamine

Metenamina (DCIT) is known as Methenamine in the US.

International Drug Name Search

Glossary

DCITDenominazione Comune Italiana

Click for further information on drug naming conventions and International Nonproprietary Names.

Friday, 15 July 2011

Tositumomab




In the US, Tositumomab (tositumomab systemic) is a member of the following drug classes: CD20 monoclonal antibodies, radiologic conjugating agents.

US matches:

  • Tositumomab

  • Tositumomab Intravenous

  • Tositumomab and Iodine 131I-Tositumomab

Scheme

Rec.INN

ATC (Anatomical Therapeutic Chemical Classification)

L01XC,V09X,V10XA53

CAS registry number (Chemical Abstracts Service)

0208921-02-2

Chemical Formula

C6416-H9874-N1688-O1987-S44

Molecular Weight

143860

Therapeutic Categories

Antineoplastic agent

Immunomodulator

Monoclonal antibody

Chemical Name

Immunoglobulin G2a anti-(human antigen CD 20) (mouse monoclonal clone B1R1 gamma 2a-chain), disulfide with mouse monoclonal clone B1R1 £ x-chain, dimer

Foreign Names

  • Tositumomabum (Latin)
  • Tositumomab (German)
  • Tositumomab (French)
  • Tositumomab (Spanish)

Generic Names

  • US 5595721 (IS)
  • CD-20-iodine 131 (IS)
  • SB-393229 (IS)
  • Tositumomab iodine 131I (IS)

Brand Names

  • Bexxar
    GlaxoSmithKline, Canada; GlaxoSmithKline, United States


  • Iodine 131I-Tositumomab
    MDS Nordion, United States


  • Tositumomab
    McKesson, United States

International Drug Name Search

Glossary

ISInofficial Synonym
Rec.INNRecommended International Nonproprietary Name (World Health Organization)

Click for further information on drug naming conventions and International Nonproprietary Names.

Sunday, 10 July 2011

Visnadine




In some countries, this medicine may only be approved for veterinary use.

Scheme

Rec.INN

ATC (Anatomical Therapeutic Chemical Classification)

C04AX24

CAS registry number (Chemical Abstracts Service)

0000477-32-7

Chemical Formula

C21-H24-O7

Molecular Weight

388

Therapeutic Category

Vasodilator

Chemical Name

Butanoic acid, 2-methyl-, 10-(acetyloxy)-9,10-dihydro-8,8-dimethyl-2-oxo-2H,8H-benzo[1,2-b:3,4-b']dipyran-9-yl ester, [9R-[9α(R*),10α]]-

Foreign Names

  • Visnadinum (Latin)
  • Visnadin (German)
  • Visnadine (French)
  • Visnadina (Spanish)

Brand Name

  • Isonergine (veterinary use)
    Merial, France

International Drug Name Search

Glossary

Rec.INNRecommended International Nonproprietary Name (World Health Organization)

Click for further information on drug naming conventions and International Nonproprietary Names.

Saturday, 2 July 2011

Perdophen pediatrie




Perdophen pediatrie may be available in the countries listed below.


Ingredient matches for Perdophen pediatrie



Ibuprofen

Ibuprofen is reported as an ingredient of Perdophen pediatrie in the following countries:


  • Belgium

International Drug Name Search

Monday, 20 June 2011

Kofron




Kofron may be available in the countries listed below.


Ingredient matches for Kofron



Clarithromycin

Clarithromycin is reported as an ingredient of Kofron in the following countries:


  • Spain

International Drug Name Search

Monday, 13 June 2011

Losamel




Losamel may be available in the countries listed below.


Ingredient matches for Losamel



Omeprazole

Omeprazole is reported as an ingredient of Losamel in the following countries:


  • Ireland

International Drug Name Search

Friday, 10 June 2011

Anesketin




Anesketin may be available in the countries listed below.


In some countries, this medicine may only be approved for veterinary use.

Ingredient matches for Anesketin



Ketamine

Ketamine is reported as an ingredient of Anesketin in the following countries:


  • Luxembourg

Ketamine hydrochloride (a derivative of Ketamine) is reported as an ingredient of Anesketin in the following countries:


  • Belgium

International Drug Name Search

Monday, 6 June 2011

Extinosad




Extinosad may be available in the countries listed below.


In some countries, this medicine may only be approved for veterinary use.

Ingredient matches for Extinosad



Chlorhexidine

Chlorhexidine digluconate (a derivative of Chlorhexidine) is reported as an ingredient of Extinosad in the following countries:


  • Australia

Spinosad

Spinosad is reported as an ingredient of Extinosad in the following countries:


  • Australia

  • New Zealand

International Drug Name Search

Tuesday, 24 May 2011

Retisert eent


Generic Name: Fluocinolone Acetonide eent
Class: Corticosteroids
Chemical Name: (6α,11β,16α) - 6,9 - Difluoro - 11,21 - dihydroxy - 16,17 - [(1 - methylethylidene)bis(oxy)] - pregna - 1,4 - diene - 3,20 - dione
Molecular Formula: C24H30F2O6

Introduction

Synthetic fluorinated corticosteroid.1


Uses for Retisert


Uveitis


Management of chronic noninfectious uveitis affecting the posterior segment of the eye (designated an orphan drug by FDA for this use).1 2 4


Retisert Dosage and Administration


Administration


Ophthalmic Administration


Surgically implant intravitreally through a pars plana incision into posterior segment of eye.1


Maintain aseptic technique prior to and during the procedure to ensure sterility of the surgical field and implants.1 Do not resterilize implants by any method.1


Handle implants only by the suture tab to avoid damaging the implant; damage may increase rate of drug release.1


Avoid simultaneous implantation into both eyes in order to minimize risk of bilateral postoperative infections.1


Following depletion of fluocinolone acetonide from the implant, may remove the implant and replace with a new one to continue therapy.1


During implantation and explantation, avoid applying sheer forces on the implant that could disengage the silicone cup reservoir from the suture tab.1


Dosage


Available as fluocinolone acetonide; dosage expressed in terms of the salt.1


Pediatric Patients


Uveitis

Ophthalmic

Children ≥12 years of age: 0.59 mg (1 implant) in affected eye(s) approximately every 30 months.1 3


Adults


Uveitis

Ophthalmic

0.59 mg (1 implant) in affected eye(s) approximately every 30 months.1 3


Cautions for Retisert


Contraindications



  • Viral diseases of the cornea and conjunctiva (e.g., epithelial herpes simplex keratitis [dendritic keratitis], vaccinia, varicella).1




  • Mycobacterial infection of the eye.1




  • Fungal diseases of ocular structures.1




  • Known or suspected hypersensitivity to fluocinolone acetonide, other corticosteroids, or any ingredient in the formulation.1



Warnings/Precautions


Warnings


Surgical Complications

Potential complications accompanying insertion of the implant may include cataract formation, choroidal or retinal detachment, temporary decrease in visual acuity, endophthalmitis, hypotony, increased intraocular pressure (IOP), exacerbation of intraocular inflammation, vitreous hemorrhage, vitreous loss, and wound dehiscence.1


Immediate and temporary decrease in visual acuity in the implanted eye will occur in most patients and may persist for 1–4 weeks after implantation.1


Increased Intraocular Pressure

Risk of glaucoma with prolonged use of corticosteroids; monitor periodically for elevated IOP (e.g., every 3–6 months, more frequently in immediate postimplantation period).1 3 Use with caution in the presence of glaucoma.1


Approximately 60% of patients expected to require drug therapy to reduce IOP within 34 weeks after implantation.1 Within 2 years of implantation, 32% of patients expected to require filtering procedures for IOP control.1


Immunosuppressive Effects

Risk of prolongation or exacerbation of ocular viral infections (e.g., herpes simplex) with ophthalmic corticosteroids.1 Use with extreme caution in patients with history of herpes simplex.1


Risk of secondary ocular infection (bacterial, fungal, or viral) with prolonged use of corticosteroids.1 Consider possibility of fungal infection if persistent corneal ulceration occurs.1


In acute purulent conditions, corticosteroids may mask or enhance existing infections.1


Wound Healing Complications

Use of ophthalmic corticosteroids after cataract surgery may delay healing and increase bleb formation.1


General Precautions


Proper Handling of Implants

Exercise caution in order to maintain sterility of and avoid damage to the implant.1 (See Administration under Dosage and Administration.)


Specific Populations


Pregnancy

Category C.1


Lactation

Caution if used in nursing women.1 Not known whether ocular administration of corticosteroids could result in sufficient systemic absorption to produce detectable quantities in milk.1


Systemically administered corticosteroids appear in milk and could suppress growth, interfere with endogenous corticosteroid production, or cause other adverse effects.


Pediatric Use

Safety and efficacy not established in children <12 years of age.1


Geriatric Use

No substantial differences in safety and efficacy relative to younger adults.1


Common Adverse Effects


Cataracts, increased IOP, ocular pain, and surgical complications (e.g., cataract fragments in the eye, injury, mechanical complications, migration or expulsion of implant; wound complications or wound dehiscence) reported in 50–90% of patients.1


Reduced visual acuity, conjunctival hemorrhage or hyperemia, glaucoma, blurred vision, abnormal sensation in the eye, ocular irritation or inflammation, hypotony, pruritus, vitreous floaters or hemorrhage, ptosis, maculopathy, eyelid edema, increased tearing, and dry eye reported in 10–35% of patients.1


Headache was most frequent systemic effect.1


Interactions for Retisert


No formal drug interaction studies have been performed to date.3 However, because of limited systemic exposure, only intraocular interactions would be expected.3


Retisert Pharmacokinetics


Absorption


Bioavailability


Implant is designed to release fluocinolone acetonide locally to the posterior segment of the eye at a nominal initial rate of 0.6 mcg daily, decreasing over the first month to steady state of 0.3–0.4 mcg daily for approximately 30 months.1


Concentrations of the drug in aqueous and vitreous humor highly variable 1


Limited systemic exposure following intravitreal implantation; plasma concentrations are usually undetectable.1


Stability


Storage


Ophthalmic


Implant

15–25°C. Protect from freezing.1


ActionsActions



  • Corticosteroids inhibit edema, fibrin deposition, capillary dilation, leukocyte migration, capillary and fibroblast proliferation, deposition of collagen, and scar formation associated with inflammation.1




  • Mechanism of ocular effects is unknown.1 Corticosteroids may induce phospholipase A2 inhibitory proteins; these proteins may inhibit release of arachidonic acid, thus controlling biosynthesis of potent mediators of inflammation (e.g., prostaglandins, leukotrienes).1



Advice to Patients



  • Importance of informing patients that fluocinolone acetonide treats ocular inflammation only and does not treat underlying disease.1




  • Importance of advising patients to return to clinician’s office for follow-up ophthalmologic examinations of both eyes at appropriate intervals following insertion of the implant.1




  • Importance of explaining risks of surgical complications, adverse ocular effects, and ocular infections.1




  • Importance of women informing clinicians if they are or plan to become pregnant or plan to breast-feed.1




  • Importance of informing clinicians of existing or contemplated concomitant therapy, including prescription and OTC drugs, as well as any concomitant illnesses, especially glaucoma or existing bacterial, viral, or fungal infections of the eye.1




  • Importance of informing patients of other important precautionary information.1 (See Cautions.)



Preparations


Excipients in commercially available drug preparations may have clinically important effects in some individuals; consult specific product labeling for details.













Fluocinolone Acetonide

Routes



Dosage Forms



Strengths



Brand Names



Manufacturer



Ophthalmic



Implants



0.59 mg



Retisert



Bausch & Lomb


Comparative Pricing


This pricing information is subject to change at the sole discretion of DS Pharmacy. This pricing information was updated 03/2011. Actual costs to patients will vary depending on the use of specific retail or mail-order locations and health insurance copays.


Fluocinonide 0.05% Cream (TEVA PHARMACEUTICALS USA): 30/$12.99 or 90/$36.97


Fluocinonide 0.05% Cream (TEVA PHARMACEUTICALS USA): 15/$11.99 or 45/$22.97


Fluocinonide 0.05% Cream (FOUGERA): 60/$14.99 or 180/$26.97


Fluocinonide 0.05% Gel (FOUGERA): 60/$37.99 or 180/$105.97


Fluocinonide 0.05% Gel (TARO): 30/$23.99 or 90/$67.97


Fluocinonide 0.05% Gel (FOUGERA): 15/$17.99 or 45/$49.97


Fluocinonide 0.05% Ointment (TARO): 60/$33.99 or 180/$90.96


Fluocinonide 0.05% Ointment (TARO): 15/$19.99 or 45/$54.97


Fluocinonide 0.05% Ointment (TEVA PHARMACEUTICALS USA): 30/$23.99 or 90/$67.97


Fluocinonide 0.05% Solution (TARO): 20/$23.99 or 40/$39.98


Fluocinonide 0.05% Solution (TEVA PHARMACEUTICALS USA): 60/$22.99 or 180/$64.99


Fluocinonide-E 0.05% Cream (TEVA PHARMACEUTICALS USA): 60/$17.99 or 180/$50.96


Fluocinonide-E 0.05% Cream (TEVA PHARMACEUTICALS USA): 30/$15.99 or 90/$41.97


Fluocinonide-E 0.05% Cream (TEVA PHARMACEUTICALS USA): 15/$16.99 or 45/$36.97


Vanos 0.1% Cream (MEDICIS): 30/$179.99 or 90/$499.97


Vanos 0.1% Cream (MEDICIS): 60/$280.99 or 180/$780.97



Disclaimer

This report on medications is for your information only, and is not considered individual patient advice. Because of the changing nature of drug information, please consult your physician or pharmacist about specific clinical use.


The American Society of Health-System Pharmacists, Inc. and Drugs.com represent that the information provided hereunder was formulated with a reasonable standard of care, and in conformity with professional standards in the field. The American Society of Health-System Pharmacists, Inc. and Drugs.com make no representations or warranties, express or implied, including, but not limited to, any implied warranty of merchantability and/or fitness for a particular purpose, with respect to such information and specifically disclaims all such warranties. Users are advised that decisions regarding drug therapy are complex medical decisions requiring the independent, informed decision of an appropriate health care professional, and the information is provided for informational purposes only. The entire monograph for a drug should be reviewed for a thorough understanding of the drug's actions, uses and side effects. The American Society of Health-System Pharmacists, Inc. and Drugs.com do not endorse or recommend the use of any drug. The information is not a substitute for medical care.

AHFS Drug Information. © Copyright, 1959-2011, Selected Revisions June 2006. American Society of Health-System Pharmacists, Inc., 7272 Wisconsin Avenue, Bethesda, Maryland 20814.




References



1. Bausch & Lomb Incorporated. Retisert (fluocinolone acetonide intravitreal implant) 0.59 mg prescribing information. Rochester, NY; 2005 Apr.



2. Bausch & Lomb. Retisert (fluocinolone acetonide intravitreal implant) 0.59 mg formulary kit. Tampa, FL; 2005 May.



3. Bausch & Lomb, Rochester, NY: Personal communication.



4. Food and Drug Administration. Orphan designation pursuant to Section 526 of the Federal Food and Cosmetic Act as amended by the Orphan Drug Act (P.L. 97-414). Rockville, MD. From FDA website ().



More Retisert eent resources


  • Retisert eent Side Effects (in more detail)
  • Retisert eent Use in Pregnancy & Breastfeeding
  • Retisert eent Drug Interactions
  • Retisert eent Support Group
  • 2 Reviews for Retisert eent - Add your own review/rating


Compare Retisert eent with other medications


  • Uveitis

Monday, 23 May 2011

Atiten




Atiten may be available in the countries listed below.


Ingredient matches for Atiten



Dihydrotachysterol

Dihydrotachysterol is reported as an ingredient of Atiten in the following countries:


  • Italy

International Drug Name Search

Saturday, 21 May 2011

Amlodipina Farmoz




Amlodipina Farmoz may be available in the countries listed below.


Ingredient matches for Amlodipina Farmoz



Amlodipine

Amlodipine is reported as an ingredient of Amlodipina Farmoz in the following countries:


  • Portugal

International Drug Name Search

Friday, 20 May 2011

Pravalip




Pravalip may be available in the countries listed below.


Ingredient matches for Pravalip



Pravastatin

Pravastatin sodium salt (a derivative of Pravastatin) is reported as an ingredient of Pravalip in the following countries:


  • Colombia

  • Germany

  • Israel

International Drug Name Search

Monday, 9 May 2011

Ultracain Suprarenin




Ultracain Suprarenin may be available in the countries listed below.


Ingredient matches for Ultracain Suprarenin



Articaine

Articaine hydrochloride (a derivative of Articaine) is reported as an ingredient of Ultracain Suprarenin in the following countries:


  • Germany

Epinephrine

Epinephrine hydrochloride (a derivative of Epinephrine) is reported as an ingredient of Ultracain Suprarenin in the following countries:


  • Germany

International Drug Name Search

Saturday, 7 May 2011

Vioridon




Vioridon may be available in the countries listed below.


Ingredient matches for Vioridon



Baclofen

Baclofen is reported as an ingredient of Vioridon in the following countries:


  • Greece

International Drug Name Search

Thursday, 28 April 2011

Aerovial




Aerovial may be available in the countries listed below.


Ingredient matches for Aerovial



Budesonide

Budesonide is reported as an ingredient of Aerovial in the following countries:


  • Chile

International Drug Name Search

Sunday, 24 April 2011

Ivemend




Ivemend may be available in the countries listed below.


UK matches:

  • IVEMEND 115 mg powder for solution for infusion
  • IVEMEND 115 mg powder for solution for infusion (SPC)
  • IVEMEND 150 mg powder for solution for infusion (SPC)

Ingredient matches for Ivemend



Fosaprepitant

Fosaprepitant is reported as an ingredient of Ivemend in the following countries:


  • Denmark

  • Slovenia

Fosaprepitant dimeglumine (a derivative of Fosaprepitant) is reported as an ingredient of Ivemend in the following countries:


  • Austria

  • France

  • Germany

  • Greece

  • Norway

  • Switzerland

  • United Kingdom

International Drug Name Search

Glossary

SPC Summary of Product Characteristics (UK)

Click for further information on drug naming conventions and International Nonproprietary Names.

Monday, 18 April 2011

Loratadin-1A Pharma




Loratadin-1A Pharma may be available in the countries listed below.


Ingredient matches for Loratadin-1A Pharma



Loratadine

Loratadine is reported as an ingredient of Loratadin-1A Pharma in the following countries:


  • Austria

  • Germany

International Drug Name Search

Tuesday, 12 April 2011

Uronid




Uronid may be available in the countries listed below.


Ingredient matches for Uronid



Flavoxate

Flavoxate hydrochloride (a derivative of Flavoxate) is reported as an ingredient of Uronid in the following countries:


  • Spain

International Drug Name Search

Tuesday, 5 April 2011

Esertia Paranova




Esertia Paranova may be available in the countries listed below.


Ingredient matches for Esertia Paranova



Escitalopram

Escitalopram oxalate (a derivative of Escitalopram) is reported as an ingredient of Esertia Paranova in the following countries:


  • Denmark

International Drug Name Search

Monday, 28 March 2011

Tebantin




Tebantin may be available in the countries listed below.


Ingredient matches for Tebantin



Gabapentin

Gabapentin is reported as an ingredient of Tebantin in the following countries:


  • Georgia

  • Russian Federation

International Drug Name Search

Thursday, 24 March 2011

Carbiquinone




Carbiquinone may be available in the countries listed below.


Ingredient matches for Carbiquinone



Ubidecarenone

Ubidecarenone is reported as an ingredient of Carbiquinone in the following countries:


  • Japan

International Drug Name Search

Tuesday, 22 March 2011

Diflunisal


Pronunciation: dye-FLOO-ni-sal
Generic Name: Diflunisal
Brand Name: Dolobid

Diflunisal is a nonsteroidal anti-inflammatory drug (NSAID). It may cause an increased risk of serious and sometimes fatal heart and blood vessel problems (eg, heart attack, stroke). The risk may be greater if you already have heart problems or if you take Diflunisal for a long time. Do not use Diflunisal right before or after bypass heart surgery.


Diflunisal may cause an increased risk of serious and sometimes fatal stomach ulcers and bleeding. Elderly patients may be at greater risk. This may occur without warning signs.





Diflunisal is used for:

Treating rheumatoid arthritis, osteoarthritis, or mild to moderate pain. It may also be used for other conditions as determined by your doctor.


Diflunisal is an NSAID. Exactly how it works is not known. It may block certain substances in the body that are linked to inflammation. NSAIDs treat the symptoms of pain and inflammation. They do not treat the disease that causes those symptoms.


Do NOT use Diflunisal if:


  • you are allergic to any ingredient in Diflunisal

  • you have had a severe allergic reaction (eg, severe rash, hives, trouble breathing, growths in the nose, dizziness) to aspirin or an NSAID (eg, ibuprofen, celecoxib)

  • you have recently had or will be having bypass heart surgery

  • you are also taking another NSAID (eg, ibuprofen)

  • you are in the last 3 months of pregnancy

Contact your doctor or health care provider right away if any of these apply to you.



Before using Diflunisal:


Some medical conditions may interact with Diflunisal. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:


  • if you are pregnant, planning to become pregnant, or are breast-feeding

  • if you are taking any prescription or nonprescription medicine, herbal product, or dietary supplement

  • if you have allergies to medicines, foods, or other substances

  • if you have a history of kidney or liver disease, diabetes, or stomach or bowel problems (eg, bleeding, perforation, ulcers)

  • if you have a history of swelling or fluid buildup, asthma, growths in the nose (nasal polyps), or mouth inflammation

  • if you have high blood pressure, blood disorders, bleeding or clotting problems, heart problems (eg, heart failure), or blood vessel disease, or if you are at risk for any of these diseases

  • if you have chickenpox, the flu, poor health, dehydration or low fluid volume, or low blood sodium levels, you drink alcohol, or you have a history of alcohol abuse

Some MEDICINES MAY INTERACT with Diflunisal. Tell your health care provider if you are taking any other medicines, especially any of the following:


  • Anticoagulants (eg, warfarin), aspirin, corticosteroids (eg, prednisone), heparin, or selective serotonin reuptake inhibitors (SSRIs) (eg, fluoxetine) because risk of stomach bleeding may be increased

  • Antacids, other NSAIDs (eg, ibuprofen), or probenecid because they may increase the risk of Diflunisal's side effects

  • Acetaminophen, cyclosporine, lithium, methotrexate, quinolones (eg, ciprofloxacin), or sulfonylureas (eg, glipizide) because the risk of their side effects may be increased by Diflunisal

  • Angiotensin-converting enzyme (ACE) inhibitors (eg, enalapril), angiotensin receptor blockers (eg, losartan), or diuretics (eg, furosemide, hydrochlorothiazide) because their effectiveness may be decreased by Diflunisal

This may not be a complete list of all interactions that may occur. Ask your health care provider if Diflunisal may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.


How to use Diflunisal:


Use Diflunisal as directed by your doctor. Check the label on the medicine for exact dosing instructions.


  • Diflunisal comes with an extra patient information sheet called a Medication Guide. Read it carefully. Read it again each time you get Diflunisal refilled.

  • Take Diflunisal by mouth. It may be taken with food if it upsets your stomach. Taking it with food may not lower the risk of stomach or bowel problems (eg, bleeding, ulcers). Talk with your doctor or pharmacist if you have persistent stomach upset.

  • Swallow Diflunisal whole. Do not break, crush, or chew before swallowing.

  • Take Diflunisal with a full glass of water (8 oz/240 mL) as directed by your doctor.

  • If you miss a dose of Diflunisal and you are taking it regularly, take it as soon as possible. If it is almost time for your next dose, skip the missed dose. Go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about the proper use of Diflunisal.



Important safety information:


  • Diflunisal may cause dizziness or drowsiness. These effects may be worse if you take it with alcohol or certain medicines. Use Diflunisal with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.

  • Serious stomach ulcers or bleeding can occur with the use of Diflunisal. Taking it in high doses, for a long time, smoking, or drinking alcohol increases the risk of these side effects. Taking Diflunisal with food will NOT reduce the risk of these effects. If you have severe stomach or back pain; black, tarry stools; vomit that looks like blood or coffee grounds; or unusual weight gain or swelling, contact your doctor or emergency room right away.

  • Do NOT take more than the recommended dose or use for longer than prescribed without checking with your doctor.

  • Diflunisal is an NSAID. Before you start any new medicine, check the label to see if it has an NSAID (eg, ibuprofen) in it too. If it does or if you are not sure, check with your doctor or pharmacist.

  • Do not take aspirin while you are using Diflunisal unless your doctor tells you to.

  • Diflunisal may interfere with certain lab tests. Be sure your doctor and lab personnel know that you take Diflunisal.

  • Aspirin has been linked to a serious illness called Reye Syndrome. Do not give Diflunisal to a child or teenager who has the flu, chickenpox, or a viral infection. Contact your doctor with any questions or concerns.

  • Lab tests, including kidney function, complete blood cell counts, and blood pressure, may be performed while you use Diflunisal. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.

  • Use Diflunisal with caution in the ELDERLY; they may be more sensitive to its effects, especially stomach bleeding and kidney problems.

  • Diflunisal should not be used in CHILDREN younger than 12 years old; safety and effectiveness in these children have not been confirmed.

  • PREGNANCY and BREAST-FEEDING: Diflunisal may cause harm to the fetus. Do not use it during the last 3 months of pregnancy. If you think you may be pregnant, contact your doctor. You will need to discuss the benefits and risks of using Diflunisal while you are pregnant. Diflunisal is found in breast milk. Do not breast-feed while taking Diflunisal.


Possible side effects of Diflunisal:


All medicines can cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:



Constipation; diarrhea; dizziness; drowsiness; gas; headache; heartburn; nausea; stomach upset.



Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; trouble breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); bloody or black, tarry stools; change in the amount of urine produced; chest pain; confusion; dark urine; depression; fainting; fast or irregular heartbeat; fever, chills, or persistent sore throat; mental or mood changes; numbness of an arm or leg; one-sided weakness; red, swollen, blistered, or peeling skin; ringing in the ears; seizures; severe headache or dizziness; severe or persistent stomach pain or nausea; severe vomiting; shortness of breath; sudden or unexplained weight gain; swelling of hands, legs, or feet; unusual bruising or bleeding; unusual joint or muscle pain; unusual tiredness or weakness; vision or speech changes; vomit that looks like coffee grounds; yellowing of the skin or eyes.



This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.


See also: Diflunisal side effects (in more detail)


If OVERDOSE is suspected:


Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include confusion; decreased urination; increased sweating; loss of consciousness; ringing in the ears; seizures; severe dizziness or drowsiness; severe nausea or stomach pain; slow, fast, or troubled breathing; unusual bleeding or bruising; vomit that looks like coffee grounds.


Proper storage of Diflunisal:

Store Diflunisal at room temperature, between 59 and 86 degrees F (15 and 30 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Diflunisal out of the reach of children and away from pets.


General information:


  • If you have any questions about Diflunisal, please talk with your doctor, pharmacist, or other health care provider.

  • Diflunisal is to be used only by the patient for whom it is prescribed. Do not share it with other people.

  • If your symptoms do not improve or if they become worse, check with your doctor.

  • Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about Diflunisal. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.



Issue Date: February 1, 2012

Database Edition 12.1.1.002

Copyright © 2012 Wolters Kluwer Health, Inc.

More Diflunisal resources


  • Diflunisal Side Effects (in more detail)
  • Diflunisal Use in Pregnancy & Breastfeeding
  • Drug Images
  • Diflunisal Drug Interactions
  • Diflunisal Support Group
  • 5 Reviews for Diflunisal - Add your own review/rating


  • Diflunisal Prescribing Information (FDA)

  • Diflunisal Monograph (AHFS DI)

  • Diflunisal Professional Patient Advice (Wolters Kluwer)

  • diflunisal Concise Consumer Information (Cerner Multum)

  • diflunisal Advanced Consumer (Micromedex) - Includes Dosage Information



Compare Diflunisal with other medications


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  • Rheumatoid Arthritis